David Sauer

David Sauer is a biophysicist focusing on the structure and function of membrane channels and transporters. As group leader at the University of Oxford since 2021, he has been studying the structure and function of membrane proteins for 21 years. David completed his graduate degree studying potassium channel structure and ion selectivity with Youxing Jiang at the University of Texas Southwestern Medical Center. This was followed by postdoctoral training with Da-Neng Wang at New York University School of Medicine. There, he described the structure, transport mechanism, and chemical inhibition of SLC13/DASS membrane transporters. Since joining Oxford's CMD, David has led a group studying membrane proteins' function, pathogenesis, and chemical targeting by small molecules. Among the target he has described are the amino acid transporters and viral receptors CAT1 and ACE2-SIT1. His group has also revealed the ping-pong reaction mechanism, and product-bound inhibited state of the ceramide s