Klaus Gerwert

Klaus Gerwert is actively advancing the development and application of time-resolved infrared difference spectroscopy in protein research in over 260 publications with over 18,000 citations and several patents. He is internationally recognized for his pioneering studies on protein reaction mechanisms, especially for his discovery of the catalytic role of internal water molecules in protein function. Recently, he invented quantum cascade laser-based IR imaging of cancer and brain tissue in combination with AI as a "label-free digital pathology" approach. His current focus is on translation of the immuno-IR sensor he invented into the clinic. This approach uses the degree of misfolding of a biomarker as a measure instead of its concentration. As a result, the risk of symptom-free individuals progressing to a clinical stage of Alzheimer's can be determined in advance with a simple blood test. This sensor measures the degree of misfolding of a biomarker instead of its concentrati