Madeleine Barrett
NIH/NCATS
Madeleine Barrett is listed at NIH/NCATS. Madeleine is scheduled to speak at SLAS 2027 International Conference & Exhibition on 3 February 2027.
Compiled from published conference agendas; not yet confirmed by Madeleine. Is this you? Claim this profile.
About
Madeleine Barrett is a fourth-year PhD student in a joint doctoral program with NIH/NCATS and Karolinska Institutet in Sweden. Her research focuses on developing novel inhibitors for a particularly challenging target class. The glutathione peroxidases GPX1 and GPX4 are selenoproteins with critical roles in cellular redox balance and have been implicated in tumor progression and treatment resistance. As part of her doctoral research, Madeleine conducted a high-throughput screen of more than 200,000 compounds using a newly developed GPX screening pipeline, leading to the identification of highly potent GPX1 inhibitors. She is particularly enthusiastic about assay development and has developed several novel lysate- and cell-based assays for hit characterization and mechanistic studies. Madeleine plans to defend her PhD in 2027 and hopes to continue developing innovative approaches to tackle difficult-to-drug targets in the next stage of her career.