Shannon Buckley
Associate Professor, University of Utah
Shannon Buckley is listed as Associate Professor, University of Utah. Shannon is scheduled to speak at SLAS 2027 International Conference & Exhibition on 1 February 2027.
Compiled from published conference agendas; not yet confirmed by Shannon. Is this you? Claim this profile.
About
University of St. Thomas, St. Paul, MN B.S. 05/2000 Biology University of Minnesota, Minneapolis, MN Ph.D. 01/2009 Molecular and Cellular Biology NYU School of Medicine, New York, NY Postdoctoral 04/2015 Cancer and Stem Cell Biology The Buckley Lab investigates how dysregulation of the ubiquitin–proteasome system drives hematologic malignancies with a focus on ubiquitin E3 ligases. A central theme of the lab is defining how aberrant protein ubiquitylation alters pathways such as PI3K, DNA damage responses, cell cycle control, and RNA splicing to promote leukemogenesis and lymphomagenesis. Using integrated multi-omics approaches in human samples and innovative mouse models, the lab studies the roles of E3 ligases including FBXO21, UBR5, and FBXL6 in acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and mantle cell lymphoma (MCL). Through these efforts, the lab aims to uncover fundamental mechanisms of hematopoietic regulation and identify novel, mechanism-based therapies fo