Alexey Zakharov

Dr. Alexey Zakharov is the informatics group leader in an early therapeutic discovery project team within NCATS’ Division of Preclinical Innovation, where he manages and coordinates the team’s efforts to achieve project deliverables and milestones. The main goal of his group research program is to utilize computational methods and ML/AI-based approaches to accelerate screening and discovery campaigns, and to contribute comprehensive analysis and modeling techniques to data generated for small molecule development projects. He oversees the proper application of cheminformatics techniques and targeted molecular design to deliver compounds with improved properties, having better selectivity and safety margins. Dr. Alexey Zakharov is involved in more than 50 active probe discovery projects focused on cancer and cardiovascular, neurological, viral and inflammatory diseases. He received his PhD in bioinformatics from the Institute of Biomedical Chemistry (IBMC) in 2008.