Charles Johannes

Charlie Johannes is the Founder, President, and Chief Scientist at EPOC Scientific, CO-founder, VP and board member of the Peptide Drug Hunting Consortium, and former Vice President of Exploratory Chemistry at Fog Pharmaceuticals, where he helped pioneer the development of hyper-stabilized helical peptides (Helicons™). With over 25 years of experience as a drug hunter and platform innovator, Charlie has led efforts in novel modality design, medicinal chemistry, and chemistry-enabled therapeutic platforms across industry and academia. At EPOC, he advises biotech startups, RLT companies, and venture firms on peptide therapeutics and translational strategy, with clients including Unnatural Products, 48Hour Discovery, Atommap, and others. Previously, he served as Head of Organic Chemistry at ASTAR in Singapore, where he led national peptide drug discovery initiatives, secured over $60 million in funding, and forged a landmark collaboration with Merck. He also held key scientific leadership