Chi-Lik Ken Lee

Dr. Chi-Lik Ken Lee is the Division Director of Digital Chemistry at A*STAR’s Institute of Sustainability for Chemicals, Energy and Environment (ISCE2). A synthetic organic chemist by training, he brings over 20 years of expertise across the pharmaceutical, academic, and industrial sectors. Ken specializes in high-throughput experimentation (HTE) and AI-driven chemical synthesis. At ISCE2, he leads the development of integrated HTE discovery workflows that utilize state-of-the-art automation and analytics. By transforming traditional R&D bottlenecks into rapid, autonomous cycles, these workflows drastically reduce hit-to-lead times and enhance predictive modeling, empowering the accelerated discovery of novel small molecules. Previously, Ken spearheaded the high-throughput organic synthesis team at S*Bio Pte Ltd, contributing to an FDA-approved drug. With over 40 publications and 10 patents, his extensive experience includes consulting on deploying automated HTE laboratories to dri