Harsharan Bhatia

Dr. Harsharan S. Bhatia is a scientist specializing in spatial biology, tissue imaging, multi-omics, and translational disease research. He currently leads discovery biology initiatives at Deep Piction GmbH in Munich and maintains an academic research affiliation with Helmholtz Munich. His work focuses on developing technologies that connect three-dimensional tissue phenotypes with molecular information across biological scales. He is the first author of DISCO-MS, published in Cell, which integrates whole-organ tissue clearing, light-sheet microscopy, deep-learning-based image analysis, robotic region-of-interest extraction, and ultrasensitive mass spectrometry. He subsequently co-developed DISCO-seq, extending this concept toward image-guided single-cell and spatial transcriptomic profiling. His research has contributed to understanding neuroinflammation, cancer, infection, and the skull-meninges-brain axis. His current interests focus on translating spatial multi-omics, automation, a