Lynette Ongeri

Lynette is a Principal DMPK Scientist at Sygnature Discovery with over 15 years of experience in pharmaceutical R&D across the biotechnology and biopharmaceutical sectors. She specializes in small molecule drug discovery and leads a multidisciplinary team delivering in vitro ADME screening services, with particular expertise in metabolic stability, permeability, and drug-drug interaction (DDI) assessments. As the skill set lead for stability assays, Lynette works closely with internal client services and project teams to provide scientific guidance on both standard and bespoke assay designs, ensuring studies are aligned with client objectives and project requirements. In addition, she serves as the In Vitro Focus Group Lead, overseeing internal assay enhancement and validation activities to ensure they are delivered within agreed timelines. She is actively involved in discussions around future capabilities, working with the wider team to identify, evaluate, and prioritise new assay